3D-QSAR Study of Combretastatin A-4 Analogs Based on Molecular Docking
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چکیده
منابع مشابه
3D-QSAR Study of Combretastatin A-4 Analogs Based on Molecular Docking.
Combretastatin A-4 (CA-4), its analogues and their excellent antitumoral and antivascular activities, have attracted considerable interest of medicinal chemists. In this article, a docking simulation was used to identify molecules having the same binding mode as the lead compound, and 3D-QSAR models had been built by using CoMFA based on docking. As a result, these studies indicated that the QS...
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ژورنال
عنوان ژورنال: Molecules
سال: 2011
ISSN: 1420-3049
DOI: 10.3390/molecules16086684